Albumin, one of the most abundant proteins found in the bloodstream, is a protein made by the liver. It helps prevent fluid from exiting the body's blood vessels. If you have abnormal levels of albumin, it could signal issues with your liver or kidneys or it could signal nutrient deficiency.
High Albumin Higher than normal levels of albumin might indicate dehydration. Certain medications can cause abnormal levels of albumin.
Low Albumin Low albumin, or Hypoalbuminemia, can be caused by multiple conditions such as: nephrotic syndrome, malnutrition, heart failure, hepatic cirrhosis. Most cases of low albumin are caused by sudden onset or chronic inflammatory responses.
Symptoms of low albumin:
- Fluid retention
- Appetite changes
- Thinning hair
- Rapid heartbeat
- Weakness or exhaustion
- Vomiting, diarrhea, nausea
GGT, Gamma-Glutamyl Transferase, is an enzyme found throughout the body but most commonly found in the liver. High levels of GGT in the blood could be an indicator of damage to the liver or bile ducts.
Symptoms of abnormal levels of GGT:
- Nausea or vomiting
- Abnormal pain or swelling
- Weakness or fatigue
BUN, or Blood Urea Nitrogen, is an indicator of liver and kidney function. BUN measures the amount of nitrogen in your blood that comes from the waste product, urea. Urea is the main nitrogenous broken-down product of protein. Urea is made in the liver and leaves your body through urine.
High BUN levels can be caused by kidney disease, a high protein diet, an infection or fever, or thyroid issues. It can also be caused by: inflammation, dehydration, stress, GI bleed, poor circulation, or severe burns. If you have high BUN levels, this could be an indicator that you have an underlying health condition.
Low BUN levels can be caused by anabolic steroids, higher IGF-1, and/or growth hormone. Genetic deficiency, pregnancy, over hydration, low protein diet, and impaired liver function can also be the cause of a lower BUN value.
- Frequent urination
- Discolored urine
Creatinine is a chemical compound waste product that comes from the normal deterioration of muscles in the body. Normal levels of creatinine vary based on gender, body size, age, and race. This means there is no “normal” level. Creatinine can indicate how well your kidneys are functioning by how well they are filtering waste from your blood.
High Creatinine levels usually indicate there is too much creatine in the body because it is not being removed or filtered appropriately. It could mean that your kidneys are not functioning as they should. A high level of creatinine can be caused from ingesting large amounts of protein or a creatinine supplement. It can also be caused by dehydration.
Low creatinine levels could mean lower muscle mass due to aging, liver issues, pregnancy, or a muscular disease. Lower levels found in an older or underweight person should not be a cause for concern.
- Low muscle mass
- Liver disease
- Faint or dizziness
- Weight loss
ALT, or Alanine Transaminase, is an enzyme found mainly in the liver and is used to monitor liver function. ALT is excreted into the bloodstream when there is damage to the liver cells.
High ALT levels could indicate liver problems. Abnormal levels could be from hepatitis, infection, cirrhosis, liver cancer, or other liver disease.
Low levels of ALT is usually a good sign. However, in some instances, low ALT can be a result of an undiagnosed medical condition.
Total Protein measures the total amount of two classes of proteins found in the fluid of your blood - albumin and globulin.
High Total Protein levels If you have high protein levels, this may mean you have an infection such as HIV, blood cancer, or viral hepatitis.
Low Total Protein levels Having low protein could indicate health conditions such as malnutrition or malabsorption disorders. These conditions could also include liver or kidney disease.
- Mood changes
- Weakness or fatigue
- Slow healing injuries
- Getting or staying sick
Total Bilirubin refers to all of the bilirubin in your blood including unconjugated (indirect) bilirubin and conjugated (direct) bilirubin.
Low total bilirubin levels are nothing to be concerned about as they can be attributed to consuming substances like caffeine or NSAIDS
High total bilirubin levels can indicate several health issues such as bile duct problems or liver issues. Less severe conditions such as anemia, reactions to medications, gallstones, Gilbert Syndrome might also cause high levels of total bilirubin.
- Dark urine
- Weakness and lightheaded
- Chest pain
- Abdominal pain or swelling