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Cortisol, Estradiol, Total Testosterone, Total PSA, SHBG, Free Testosterone

The Men’s Complete Hormone Health At-Home Test is ideal for men looking to assess hormone balance, energy levels, and overall wellness. It’s especially beneficial for those experiencing symptoms like fatigue, low libido, weight gain, mood changes, or decreased muscle mass. By measuring key biomarkers—including cortisol, estradiol, total and free testosterone, SHBG, and PSA—this test provides valuable insights into testosterone levels, stress response, and prostate health, helping men take a proactive approach to optimizing performance and long-term health.

Cortisol: A stress hormone that regulates metabolism, energy production, and the body’s response to physical and emotional stress.

Estradiol: A form of estrogen in men that helps regulate libido, bone density, and cardiovascular health.

Total Testosterone: The primary male sex hormone responsible for muscle mass, energy, libido, and overall reproductive function.

Total PSA (Prostate-Specific Antigen): A protein produced by the prostate gland that helps assess prostate health and screen for potential abnormalities.

SHBG (Sex Hormone-Binding Globulin): A protein that binds to testosterone and controls how much active hormone is available for the body to use.

Free Testosterone: The unbound, active form of testosterone that directly supports energy, strength, libido, and overall male performance.

Men's Complete Hormone Health At-Home Lab Kit

Men's Complete Hormone Health

At-Home Men’s Hormone Test for men with symptoms of hormonal imbalance including decreased energy, libido, or fertility issues; provides diagnostic insight into testosterone, cortisol, estradiol, and related markers.

Collection Method

Quick Draw

Fast, simple, and painless upper-arm collection.

Insights Into Your health

Explore Hormone Health

The Men’s Complete Hormone Test Kit is a comprehensive at-home blood test designed to evaluate key hormones that influence energy, metabolism, strength, libido, and overall health. By measuring cortisol, estradiol, total testosterone, free testosterone, SHBG, and PSA, this test provides a complete view of hormonal balance and helps identify imbalances that may affect physical performance, mood, and reproductive health.

Why Monitor Hormone Health?

Hormones are essential chemical messengers that regulate critical functions including muscle growth, energy levels, metabolism, sexual health, and mood.

When hormone levels fall out of balance, men may experience:

  • Fatigue and decreased energy
  • Reduced muscle mass or increased body fat
  • Low libido or sexual performance issues
  • Mood changes or brain fog

Because symptoms often develop slowly and overlap with other conditions, testing is one of the most effective ways to identify underlying hormonal imbalances and take proactive steps toward improving overall well-being.

Cortisol

What it measures:
Cortisol is the body’s primary stress hormone, helping regulate metabolism, energy levels, and immune response.

If levels are high:

  • Chronic stress or anxiety
  • Weight gain (especially abdominal)
  • Poor sleep

If levels are low:

  • Fatigue
  • Low blood pressure
  • Difficulty handling stress
Estradiol (Estrogen)

What it measures:
Estradiol is a form of estrogen present in men that supports bone health, brain function, and hormonal balance.

If levels are high:

  • Increased body fat
  • Mood swings
  • Reduced libido

If levels are low:

  • Joint discomfort
  • Low bone density
  • Reduced sexual function
Total Testosterone

What it measures:
Total testosterone reflects the overall amount of testosterone in the bloodstream and is the primary marker of male hormone health.

If levels are low:

  • Fatigue
  • Decreased muscle mass
  • Low libido

If levels are high:

  • Acne
  • Mood changes
  • Potential hormonal imbalance
Free Testosterone

What it measures:
Free testosterone is the active form of testosterone available for the body to use, directly impacting energy, strength, and performance.

If levels are low:

  • Reduced strength and endurance
  • Low libido
  • Difficulty building muscle

If levels are high:

  • Irritability
  • Hormonal imbalance symptoms
SHBG (Sex Hormone-Binding Globulin)

What it measures:
SHBG is a protein that binds to testosterone and regulates how much is available in its active (free) form.

If levels are high:

  • Reduced free testosterone availability
  • Fatigue
  • Low libido

If levels are low:

  • Excess free testosterone
  • Acne or mood changes
Total PSA (Prostate-Specific Antigen)

What it measures:
PSA is a protein produced by the prostate gland and is commonly used to assess prostate health.

If levels are elevated:

  • Possible prostate inflammation or enlargement
  • Need for further medical evaluation

If levels are low/normal:

  • Typically indicates healthy prostate function

Test Anytime, Anywhere

How at-home health testing works

1

Order Your Lab Kit

Find the right test for your unique needs and receive clinic-grade sample collection kits delivered to your door.

2

Collect Your Sample

Follow the included instructions to easily collect your sample and ship it back to us using the prepaid return shipping label.

3

Review Your Results

Within days your test results and unique health insights will be available on our convenient online dashboard.

my labs direct at-home health testing digital health dashboard
4

Your Health, Empowered

Based on your results, we empower better health through treatments, prescription access, and physician consultation.

FAQs

Answering Your Questions

Who should take the Men’s Complete Hormone Test?

This test is recommended for men experiencing symptoms of hormonal imbalance such as low energy, decreased libido, mood changes, weight gain, or fertility concerns. It’s also ideal for men looking to proactively monitor testosterone levels, stress response, and overall hormone health.

Why is hormone testing important for men?

Hormones play a critical role in regulating energy, muscle mass, metabolism, mood, and sexual health. Imbalances—especially in testosterone—can significantly impact daily performance and long-term wellness, making routine testing an important tool for early detection and optimization.

When should I take this test?

For the most accurate results, it’s recommended to collect your sample in the morning, ideally before 9am, when hormone levels—especially testosterone—are at their peak.

How often should I test my hormone levels?

Testing frequency depends on your health goals. For general wellness, testing every 6–12 months is common, while men experiencing symptoms or actively managing hormone levels may benefit from testing every 3–6 months or as advised by a healthcare provider.

What does this test measure?

This comprehensive panel includes cortisol, estradiol, total testosterone, free testosterone, sex hormone-binding globulin (SHBG), and prostate-specific antigen (PSA)—providing insight into hormone balance, stress response, and prostate health.

How does at-home lab testing work?

Using a My labs Direct at-home lab test kit is quick and convenient:

  1. Order your test kit online
  2. Complete your sample collection and send the sample back to our lab in the included pre-pair shipping bag
  3. Your sample is analyzed in our certified laboratory
  4. Receive secure, easy-to-understand results online

This process allows you to assess your overall health and risk factors without scheduling a doctor’s appointment.

How accurate is at-home lab testing?

Our clinical-grade test kits are processed in our own CLIA-certified laboratory using standardized testing methods, ensuring results that are as accurate and reliable as traditional in-clinic lab tests.

How long does it take to get lab results?

Most customers receive their lab results within 1–3 business days after the sample is received and processed. Results are delivered securely through an online portal for easy access.

Can I use this test instead of seeing a doctor?

This at-home test is a powerful screening tool, but it does not replace medical advice or diagnosis. If your results are elevated, it’s important to consult with a healthcare provider for further evaluation and guidance.

What are the benefits of using an at-home lab test?

This at-home lab test kit offers several advantages:

  • Convenient testing without clinic visits
  • Early detection of serious health conditions
  • Affordable pricing with no insurance required
  • Fast and confidential results
  • Empowerment to take control of your health

It’s an easy way to stay proactive about your overall health.

Is my health information secure?

Yes. Your personal and health data is protected with advanced encryption and is fully HIPAA-compliant. Your results remain private and accessible only to you.

Can I use HSA or FSA funds to purchase the test?

In most cases, yes. Our at-home lab test kits are be eligible for purchase using HSA or FSA funds. Check with your plan provider for details.

What this Test measures

Men's complete Hormone Panel

This test provides you with a complete overview of your hormone health by identifying your hormonal patterns to determine if you are living with hormonal imbalance. The hormones within this test are specifically targeted for men.

 

Cortisol is produced by the adrenal glands and is the body’s primary stress hormone.  It enhances your brain’s use of glucose (sugar) and increases the availability of substances that repair tissues.  Its release is increased in response to stress and low blood-glucose levels. It helps regulate metabolism, affects blood pressure, and serves as an anti-inflammatory. Chronically elevated levels of cortisol are an indication a body is stressed which can make healthful eating habits difficult to maintain – the result is often stress-eating which leads to overeating and weight gain.

High cortisol levels – high cortisol levels can be caused by many underlying issues such as overactivity or cancer of the pituitary or adrenal glands, chronic stress and medication side effects. Estrogen can also increase cortisol levels in your blood.

Symptoms of high cortisol:

  • Weight gain around midsection and upper back
  • Rounding of the face
  • Acne
  • Slowed healing
  • Muscle weakness
  • Severe fatigue

Low cortisol levels low cortisol levels mean the adrenal glands aren’t making enough cortisol. This could be caused by Addison’s disease which could be caused by cancerous cells, removal of the adrenal glands, certain genetic disorders, and certain antifungal medications.

Symptoms of low cortisol:

  • Extreme fatigue
  • Weight loss
  • Dehydration
  • Decreased appetite
  • Low blood pressure
  • Depression
  • Irritability

Estradiol in men is crucial to male sexuality as it is essential for modulating libido, erectile function and spermatogenesis.  Estradiol is one hormone in a class of hormones called Estrogens. Estrogen is found in small but critical concentrations in men – it needs to be in balance with the rest of the body’s hormones, particularly testosterone, for the male body to perform at its best.

Symptoms of high estradiol in men:

  • Infertility
  • Erectile dysfunction (ED)
  • Development of female characteristics
  • Slowed growth

Symptoms of low estradiol in men:

  •  Fatigue
  • Sexual dysfunction
  • Bone loss
  • Fat accumulation

Testosterone is a sex hormone that regulates sex drive, muscle mass, bone mass, fat distribution and the production of both red blood cells and sperm in men.  It helps male features develop over time and it naturally decreases as men age.  The effects of gradually lowering testosterone levels in men are known as late-onset hypogonadism. This condition affects 4 in 10 men by the age of 45.  

Low TestosteroneLow testosterone levels are called Testosterone Deficiency (TD) or Low Testosterone (Low-T).  This condition is more common in men who are overweight or diabetic. Testosterone usually decreases with age so older men tend to have lower testosterone.  

Symptoms of low testosterone in Men: 

  • Fatigue
  • Decreased muscle mass 
  • Increased fat levels, especially belly fat
  • Overall weight gain
  • Low libido or sex drive 
  • Irritability
  • Mental fog and memory loss
  • Depression and low overall drive

PSA, or prostate-specific antigen, is a protein produced by both cancerous and noncancerous tissue in the prostate.  PSA levels are primarily tested to screen for prostate cancer in men. 

High levels of PSA could be a sign of prostate cancer, an enlarged prostate or a condition called prostatitis.  

 Symptoms of high PSA:   

  • Difficulty urinating 
  • Frequent urination, including during the night 
  • Slow urine stream 
  • Urinary incontinence 

Low levels of PSA is a sign of good prostate and overall health 

SHBG, or Sex hormone binding globulin, is a protein made by the liver that attaches itself to three sex hormones: testosterone, dihydrotestosterone and estradiol.  It is often used to evaluate men for low testosterone.

High SHBG levels indicates the protein is attaching itself to your sex hormones excessively, making testosterone less available in the body.  

High SHBG symptoms in men 

  • Infertility 
  • Decreased sperm concentration and motility 
  • Decreased sex drive 
  • Impotence 
  • Reduced testicle size 
  • Decreased body hair 

Low SHBG levels means there are potentially more free sex hormones for your body to use. 

Low SHBG symptoms in men: 

  • Fluid retention 
  • Acne 
  • Increased appetite and weight gain 
  • Increased muscle mass 

98% of the testosterone found in the body is bound to either sex-hormone binding globulin (SHBG) or albumin. This is referred to as “bound testosterone”. The other 2% that is left is known as “free testosterone”.  Free testosterone is what connects with testosterone receptors within the body’s cells. Free testosterone enables cell replication in the bones and muscles and is responsible for secondary sexual characteristics in men such as facial hair and a deeper voice.  Low levels of free testosterone can lead to poor muscle development, irritability, low sex drive and other issues. 

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